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TSHR rabbit monoclonal antibody

  • Catalog # : H00007253-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TSHR peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TSHR is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TSHR peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7253
  • GeneBank Accession#:
  • TSHR
  • Gene Name:
  • TSHR
  • Gene Alias:
  • CHNG1,LGR3,MGC75129,hTSHR-I
  • Gene Description:
  • thyroid stimulating hormone receptor
  • Gene Summary:
  • The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • seven transmembrane helix receptor,thyroid stimulating hormone receptor, isoform 2,thyrotropin receptor,thyrotropin receptor-I, hTSHR-I
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