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Last updated: 2016/12/4

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TSG101 Pre-design Chimera RNAi

  • Catalog # : H00007251-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens tumor susceptibility gene 101 (TSG101), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006292
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7251
  • Gene Name:
  • TSG101
  • Gene Alias:
  • TSG10,VPS23
  • Gene Description:
  • tumor susceptibility gene 101
  • Gene Summary:
  • The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq
  • Other Designations:
  • tumor susceptibility protein
  • Gene Pathway
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