TSG101 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of TSG101 transfected lysate using rabbit polyclonal anti-TSG101 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TSG101.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TSG101 transfected lysate using rabbit polyclonal anti-TSG101 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TSG101.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-TSG101 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-TSG101 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TSG101
Entrez GeneID
7251Gene Name
TSG101
Gene Alias
TSG10, VPS23
Gene Description
tumor susceptibility gene 101
Omim ID
601387Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq
Other Designations
tumor susceptibility protein
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Interactome
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Pathway
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Disease
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