TSN DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TSN DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MSVSEIFVELQGFLAAEQDIREEIRKVVQSLEQTAREILTLLQGVHQGAGFQDIPKRCLKAREHFGTVKTHLTSLKTKFPAEQYYRFHEHWRFVLQRLVFLAAFVVYLETETLVTREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDGLKYDVKKVEEVVYDLSIRGFNKETAAACVEK
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — TSN
Entrez GeneID
7247GeneBank Accession#
NM_004622.2Protein Accession#
NP_004613.1Gene Name
TSN
Gene Alias
BCLF-1, REHF-1, TRSLN
Gene Description
translin
Omim ID
600575Gene Ontology
HyperlinkGene Summary
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. [provided by RefSeq
Other Designations
recombination hotspot associated factor|recombination hotspot-binding protein
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