TSN polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant TSN.
Immunogen
TSN (NP_004613, 115 a.a. ~ 197 a.a) partial recombinant protein with GST tag.
Sequence
TREAVTEILGIEPDREKGFHLDVEDYLSGVLILASELSRLSVNSVTAGDYSRPLHISTFINELDSGFRLLNLKNDSLRKRYDG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.24 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TSN expression in transfected 293T cell line by TSN polyclonal antibody (A01).
Lane1:TSN transfected lysate (Predicted MW: 26.2 KDa).
Lane2:Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — TSN
Entrez GeneID
7247GeneBank Accession#
NM_004622Protein Accession#
NP_004613Gene Name
TSN
Gene Alias
BCLF-1, REHF-1, TRSLN
Gene Description
translin
Omim ID
600575Gene Ontology
HyperlinkGene Summary
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. [provided by RefSeq
Other Designations
recombination hotspot associated factor|recombination hotspot-binding protein
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