TRPC6 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human TRPC6 partial ORF ( NP_004612, 543 a.a. - 592 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ARFMAFWHASKAQSIIDANDTLKDLTKVTLGDNVKYYNLARIKWDPSDPQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
31.24
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TRPC6
Entrez GeneID
7225GeneBank Accession#
NM_004621Protein Accession#
NP_004612Gene Name
TRPC6
Gene Alias
FLJ11098, FLJ14863, FSGS2, TRP6
Gene Description
transient receptor potential cation channel, subfamily C, member 6
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq
Other Designations
transient receptor potential channel 6
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Interactome
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Disease
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