TRIP6 polyclonal antibody (A01)
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More Files
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant TRIP6.
Immunogen
TRIP6 (NP_003293, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
Sequence
MSGPTWLPPKQPEPARAPQGRAIPRGTPGPPPAHGAALQPHPRVNFCPLPSEQCYQAPGGPEDRGPAWVGSHGVLQHTQGLPADRGGLRPGSLDAEIDLL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — TRIP6
Entrez GeneID
7205GeneBank Accession#
NM_003302Protein Accession#
NP_003293Gene Name
TRIP6
Gene Alias
MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1
Gene Description
thyroid hormone receptor interactor 6
Omim ID
602933Gene Ontology
HyperlinkGene Summary
This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
OPA-interacting protein 1|thyroid receptor-interacting protein 6|zyxin related protein 1
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Interactomes
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Publication Reference
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c-Src-mediated phosphorylation of thyroid hormone receptor-interacting protein 6 (TRIP6) promotes osteoclast sealing zone formation.
McMichael BK, Meyer SM, Lee BS.
The Journal of Biological Chemistry 2010 Jun; 285(34):26641.
Application:IF, WB, Mouse, Mouse bone marrow (MBM)-derived osteoclasts, Raw 264.7 cells.
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c-Src-mediated phosphorylation of thyroid hormone receptor-interacting protein 6 (TRIP6) promotes osteoclast sealing zone formation.
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