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Last updated: 2016/10/16
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TRAF6 MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00007189-D01
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human TRAF6 protein.
  • Immunogen:
  • TRAF6 (AAH31052.1, 1 a.a. ~ 522 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TRAF6 MaxPab rabbit polyclonal antibody. Western Blot analysis of TRAF6 expression in human kidney.
  • PDF DownloadProtocol Download
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of TRAF6 transfected lysate using anti-TRAF6 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with TRAF6 MaxPab mouse polyclonal antibody (B01) (H00007189-B01).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
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  • Gene Information
  • Entrez GeneID:
  • 7189
  • Gene Name:
  • TRAF6
  • Gene Alias:
  • MGC:3310,RNF85
  • Gene Description:
  • TNF receptor-associated factor 6
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. Two alternatively spliced transcript variants encoding identical proteins have been reported. [provided by RefSeq
  • Other Designations:
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