TRAF3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
Western Blot
Lane 1: TRAF3 transfected lysate ( 64.5 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
TRAF3 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TRAF3 full-length
Host
Human
Theoretical MW (kDa)
62.59
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TRAF3 antibody (H00007187-B01) by Western Blots.
Western Blot
Lane 1: TRAF3 transfected lysate ( 64.5 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
TRAF3 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TRAF3
Entrez GeneID
7187GeneBank Accession#
NM_003300Protein Accession#
NP_003291Gene Name
TRAF3
Gene Alias
CAP-1, CD40bp, CRAF1, LAP1
Gene Description
TNF receptor-associated factor 3
Omim ID
601896Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq
Other Designations
CD40 associated protein 1|CD40 binding protein|CD40 receptor associated factor 1|LMP1 associated protein
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Interactome
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