HSP90B1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human HSP90B1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human HSP90B1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human HSP90B1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — HSP90B1
Entrez GeneID
7184GeneBank Accession#
HSP90B1Gene Name
HSP90B1
Gene Alias
ECGP, GP96, GRP94, TRA1
Gene Description
heat shock protein 90kDa beta (Grp94), member 1
Omim ID
191175Gene Ontology
HyperlinkGene Summary
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]).[supplied by OMIM
Other Designations
Tumor rejection antigen-1 (gp96)|endothelial cell (HBMEC) glycoprotein|glucose regulated protein, 94 kDa|heat shock protein 90kDa beta, member 1|tumor rejection antigen (gp96) 1
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