Products

Western Blot (Transfected lysate)

Western Blot analysis of NR2C2 expression in transfected 293T cell line by NR2C2 monoclonal antibody (M01), clone 2A5.

Lane 1: NR2C2 transfected lysate(65.414 KDa).
Lane 2: Non-transfected lysate.

Western Blot (Recombinant protein)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunoperoxidase of monoclonal antibody to NR2C2 on formalin-fixed paraffin-embedded human esophagus. [antibody concentration 3 ug/ml]

ELISA

RNAi Knockdown (Antibody validated)

Western blot analysis of NR2C2 over-expressed 293 cell line, cotransfected with NR2C2 Validated Chimera RNAi ( Cat # H00007182-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with NR2C2 monoclonal antibody (M01), clone 2A5 (Cat # H00007182-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

Entrez GeneID

7182

GeneBank Accession#

NM_003298

Protein Accession#

NP_003289

Gene Name

NR2C2

Gene Alias

TAK1, TR2R1, TR4, hTAK1

Gene Description

nuclear receptor subfamily 2, group C, member 2

Omim ID

601426

Gene Ontology

Hyperlink

Gene Summary

Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM

Other Designations

Nuclear hormone receptor TR4|OTTHUMP00000160276|TR4 nuclear hormone receptor