NR2C2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NR2C2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NR2C2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NR2C2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NR2C2
Entrez GeneID
7182GeneBank Accession#
NR2C2Gene Name
NR2C2
Gene Alias
TAK1, TR2R1, TR4, hTAK1
Gene Description
nuclear receptor subfamily 2, group C, member 2
Omim ID
601426Gene Ontology
HyperlinkGene Summary
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM
Other Designations
Nuclear hormone receptor TR4|OTTHUMP00000160276|TR4 nuclear hormone receptor
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