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NR2C2 rabbit monoclonal antibody

  • Catalog # : H00007182-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NR2C2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NR2C2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NR2C2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7182
  • GeneBank Accession#:
  • NR2C2
  • Gene Name:
  • NR2C2
  • Gene Alias:
  • TAK1,TR2R1,TR4,hTAK1
  • Gene Description:
  • nuclear receptor subfamily 2, group C, member 2
  • Gene Summary:
  • Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM
  • Other Designations:
  • Nuclear hormone receptor TR4,OTTHUMP00000160276,TR4 nuclear hormone receptor
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