NR2C1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human NR2C1 partial ORF ( NP_003288, 17 a.a. - 124 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GEIVTEQQTGQKIQIVTALDHNTQGKQFILTNHDGSTPSKVILARQDSTPGKVFLTTPDAAGVNQLFFTTPDLSAQHLQLLTDNSPDQGPNKVFDLCVVCGDKASGRH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.62
Interspecies Antigen Sequence
Mouse (82); Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NR2C1
Entrez GeneID
7181GeneBank Accession#
NM_003297Protein Accession#
NP_003288Gene Name
NR2C1
Gene Alias
TR2
Gene Description
nuclear receptor subfamily 2, group C, member 1
Omim ID
601529Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
TR2 nuclear hormone receptor|nuclear receptor subfamily 2, group C isoform|orphan nuclear receptor TR2|testicular receptor 2
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Interactome
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Disease
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