TPSAB1 DNAxPab

Catalog # H00007177-W01P

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Price

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Quantity

Size:200 ug
Price: USD $ 620.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Rabbit polyclonal antibody raised against a full-length human TPSAB1 DNA using DNAx™ Immune technology.DNAx Polyclonal Antibody,DNAx Polyclonal Antibodies,DNAx Pab,DNAx Polyclonal,DNA Immune,DNA Immunization,Immune Technology,Hard-to-Find Antibody,Hard-to-Find Antibodies,Hard-to-Find,Hard to Find,HardtoFind

    Technology

    DNAx™ Immune

    Immunogen

    Full-length human DNA

    Sequence

    MLNLLLLALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP

    Host

    Rabbit

    Reactivity

    Human

    Purification

    Protein A

    Quality Control Testing

    Antibody reactive against mammalian transfected lysate.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Transfected lysate)

    Immunofluorescence (Transfected cell)

    Flow Cytometry (Transfected cell)

  • Gene Info — TPSAB1

    Entrez GeneID

    7177

    GeneBank Accession#

    NM_003294.3

    Protein Accession#

    NP_003285.2

    Gene Name

    TPSAB1

    Gene Alias

    MCP7, TPS1, TPS2, TPSB1

    Gene Description

    tryptase alpha/beta 1

    Omim ID

    191080

    Gene Ontology

    Hyperlink

    Gene Summary

    Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq

    Other Designations

    lung tryptase|mast cell protease II|mast cell tryptase|pituitary tryptase|skin tryptase|tryptase 1|tryptase II|tryptase alpha II|tryptase beta 1|tryptase beta I|tryptase, alpha|tryptase-I|tryptase-III

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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