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TPSAB1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00007177-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TPSAB1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 30.36
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TPSAB1 antibody (H00007177-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00007177-T01
    TPSAB1 transfected lysate
    Western Blot
    QC Testing of H00007177-T01
    Lane 1: TPSAB1 transfected lysate ( 30.36 KDa).
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 7177
  • Gene Name:
  • TPSAB1
  • Gene Alias:
  • MCP7,TPS1,TPS2,TPSB1
  • Gene Description:
  • tryptase alpha/beta 1
  • Gene Summary:
  • Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq
  • Other Designations:
  • lung tryptase,mast cell protease II,mast cell tryptase,pituitary tryptase,skin tryptase,tryptase 1,tryptase II,tryptase alpha II,tryptase beta 1,tryptase beta I,tryptase, alpha,tryptase-I,tryptase-III
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