TPR (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human TPR partial ORF ( NP_003283, 1 a.a. - 98 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TPR
Entrez GeneID
7175GeneBank Accession#
NM_003292Protein Accession#
NP_003283Gene Name
TPR
Gene Alias
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Gene Description
translocated promoter region (to activated MET oncogene)
Omim ID
189940Gene Ontology
HyperlinkGene Summary
This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq
Other Designations
OTTHUMP00000033584|nuclear pore complex-associated protein TPR|nucleoprotein TPR|tumor potentiating region
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Interactome
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Pathway
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