TPR monoclonal antibody (M05), clone 1F8
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant TPR.
Immunogen
TPR (NP_003283, 1 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to TPR on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — TPR
Entrez GeneID
7175GeneBank Accession#
NM_003292Protein Accession#
NP_003283Gene Name
TPR
Gene Alias
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Gene Description
translocated promoter region (to activated MET oncogene)
Omim ID
189940Gene Ontology
HyperlinkGene Summary
This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq
Other Designations
OTTHUMP00000033584|nuclear pore complex-associated protein TPR|nucleoprotein TPR|tumor potentiating region
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Interactomes
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Pathways
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