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Last updated: 2017/12/10
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TPMT polyclonal antibody (A01)

  • Catalog # : H00007172-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length recombinant TPMT.
  • Immunogen:
  • TPMT (AAH05339, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag.
  • Sequence:
  • MDGTRTSLDIEEYSDTEVQKNQVLTLEEWQDKWVNGKTAFHQEQGHQLLKKHLDTFLKGKSGLRVFFPLCGKAVEMKWFADRGHSVVGVEISELGIQEFFTEQNLSYSEEPITEIPGTKVFKSSSGNISLYCCSIFDLPRTNIGKFDMIWDRGALVAINPGDRKCYADTMFSLLGKKFQYLLCVLSYDPTKHPGPPFYVPHAEIERLFGKICNIRRLEKVDAFEERHKSWGIDCLFEKLYLLTEK
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00007172-A01
    Western Blot detection against Immunogen (53.06 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7172
  • Gene Name:
  • TPMT
  • Gene Alias:
  • -
  • Gene Description:
  • thiopurine S-methyltransferase
  • Gene Summary:
  • This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000016076,S-adenosyl-L-methionine:thiopurine S-methyltransferase,thiopurine methyltransferase
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