TPM2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human TPM2 full-length ORF ( AAH11776, 1 a.a. - 284 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
56.98
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TPM2
Entrez GeneID
7169GeneBank Accession#
BC011776Protein Accession#
AAH11776Gene Name
TPM2
Gene Alias
AMCD1, DA1, DA2B, TMSB
Gene Description
tropomyosin 2 (beta)
Gene Ontology
HyperlinkGene Summary
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000021357|arthrogryposis multiplex congenital, distal, type 1
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Interactome
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Pathway
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Disease
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