TPM2 monoclonal antibody (M07), clone 3C8
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to TPM2 on formalin-fixed paraffin-embedded human smooth muscle. [antibody concentration 3 ug/ml]
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TPM2 is approximately 3ng/ml as a capture antibody.
Western Blot detection against Immunogen (56.98 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant TPM2.
Immunogen
TPM2 (AAH11776, 1 a.a. ~ 284 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (56.98 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to TPM2 on formalin-fixed paraffin-embedded human smooth muscle. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TPM2 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — TPM2
Entrez GeneID
7169GeneBank Accession#
BC011776Protein Accession#
AAH11776Gene Name
TPM2
Gene Alias
AMCD1, DA1, DA2B, TMSB
Gene Description
tropomyosin 2 (beta)
Gene Ontology
HyperlinkGene Summary
This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000021357|arthrogryposis multiplex congenital, distal, type 1
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Interactome
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Pathway
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Disease
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