TPI1 monoclonal antibody (M02A), clone 2C3
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant TPI1.
Immunogen
TPI1 (AAH07086.1, 1 a.a. ~ 249 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAPSRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPADTEVVCAPPTAYIDFARQKLDPKIAVAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEGLGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEFVDTINAKQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (94)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (53.13 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
TPI1 monoclonal antibody (M02A), clone 2C3. Western Blot analysis of TPI1 expression in HepG2.Western Blot (Recombinant protein)
ELISA
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Gene Info — TPI1
Entrez GeneID
7167GeneBank Accession#
BC007086Protein Accession#
AAH07086.1Gene Name
TPI1
Gene Alias
MGC88108, TPI
Gene Description
triosephosphate isomerase 1
Omim ID
190450Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
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Publication Reference
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Proteomic identification of putative biomarkers of radiotherapy resistance: a possible role for the 26S proteasome?
Smith L, Qutob O, Watson MB, Beavis AW, Potts D, Welham KJ, Garimella V, Lind MJ, Drew PJ, Cawkwell L.
Neoplasia 2009 Nov; 11(11):1194.
Application:WB-Ce, Human, MCF-7, MDA-MB-231, T-47D cells.
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Proteomic identification of putative biomarkers of radiotherapy resistance: a possible role for the 26S proteasome?
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