TPH1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TPH1 full-length
Host
Human
Theoretical MW (kDa)
48.95
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TPH1 antibody (H00007166-B01) by Western Blots.
SDS-PAGE Gel
TPH1 transfected lysate.
Western Blot
Lane 1: TPH1 transfected lysate ( 48.95 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TPH1
Entrez GeneID
7166GeneBank Accession#
NM_004179.1Protein Accession#
NP_004170.1Gene Name
TPH1
Gene Alias
MGC119994, TPH, TPRH
Gene Description
tryptophan hydroxylase 1
Omim ID
191060Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others
Other Designations
indoleacetic acid-5-hydroxylase|tryptophan 5-hydroxylase|tryptophan 5-monooxygenase|tryptophan hydroxylase (tryptophan 5-monooxygenase)
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Interactome
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Disease
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