TPH1 mouse monoclonal antibody (hybridoma)
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant TPH1.
Immunogen
TPH1 (NP_004170.1, 1 a.a. ~ 444 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MIEDNKENKDHSLERGRASLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLNDIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQYVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDALAKVSRKPSI
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactivity and specificity confirmed by ELISA and Western Blot.
Deliverables
Up to 5 positive hybridoma clones will be delivered to customer in the cryotube format.
Note
Customer should check the viability of the hybridomas within one month from the date of receipt. Fee-for-service of long term hybridoma storage can be performed upon customer's request.
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Applications
Western Blot (Transfected lysate)
Western Blot (Recombinant protein)
ELISA
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Gene Info — TPH1
Entrez GeneID
7166GeneBank Accession#
NM_004179.1Protein Accession#
NP_004170.1Gene Name
TPH1
Gene Alias
MGC119994, TPH, TPRH
Gene Description
tryptophan hydroxylase 1
Omim ID
191060Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others
Other Designations
indoleacetic acid-5-hydroxylase|tryptophan 5-hydroxylase|tryptophan 5-monooxygenase|tryptophan hydroxylase (tryptophan 5-monooxygenase)
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Interactome
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Pathway
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Disease
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