TPH1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TPH1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TPH1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TPH1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TPH1
Entrez GeneID
7166GeneBank Accession#
TPH1Gene Name
TPH1
Gene Alias
MGC119994, TPH, TPRH
Gene Description
tryptophan hydroxylase 1
Omim ID
191060Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others
Other Designations
indoleacetic acid-5-hydroxylase|tryptophan 5-hydroxylase|tryptophan 5-monooxygenase|tryptophan hydroxylase (tryptophan 5-monooxygenase)
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