TNXB purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of TNXB expression in transfected 293T cell line (H00007148-T01) by TNXB MaxPab polyclonal antibody.
Lane 1: TNXB transfected lysate(74.03 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TNXB protein.
Immunogen
TNXB (AAH33740.1, 1 a.a. ~ 673 a.a) full-length human protein.
Sequence
MRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYLLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNFRSPAGGG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TNXB expression in transfected 293T cell line (H00007148-T01) by TNXB MaxPab polyclonal antibody.
Lane 1: TNXB transfected lysate(74.03 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TNXB
Entrez GeneID
7148GeneBank Accession#
BC033740.1Protein Accession#
AAH33740.1Gene Name
TNXB
Gene Alias
HXBL, TENX, TNX, TNXB1, TNXB2, TNXBS, XB, XBS
Gene Description
tenascin XB
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000062664|growth-inhibiting protein 45|hexabrachion-like|tenascin XB1|tenascin XB2|tenascin-X
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Interactome
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Pathway
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Disease
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Publication Reference
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Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells.
Li H, Takai N, Yuge A, Furukawa Y, Tsuno A, Tsukamoto Y, Kong S, Moriyama M, Narahara H.
Cancer Letters 2010 Nov; 297(2):198.
Application：WB-Ce, Human, HHUA, Ishikawa, HEC-1B, SK-OV-3, OVCAR-3 cells.
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Comparative serum proteome analysis of human lymph node negative/positive invasive ductal carcinoma of the breast and benign breast disease controls via label-free semiquantitative shotgun technology.
Hu X, Zhang Y, Zhang A, Li Y, Zhu Z, Shao Z, Zeng R, Xu LX.
Omics 2009 Aug; 13(4):291.
Application：ELISA, Human, Serum.
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Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells.
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