TNP1 monoclonal antibody (M01), clone 1B5
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant TNP1.
Immunogen
TNP1 (AAH29516.1, 1 a.a. ~ 55 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSTSRKLKSHGMRRSKSRSPHKGVKRGGSKRKYRKGNLKSRKRGDDANRNYRSHL
Host
Mouse
Reactivity
Human
Isotype
IgG2b kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.79 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to TNP1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TNP1 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — TNP1
Entrez GeneID
7141GeneBank Accession#
BC029516Protein Accession#
AAH29516.1Gene Name
TNP1
Gene Alias
TP1
Gene Description
transition protein 1 (during histone to protamine replacement)
Omim ID
190231Gene Ontology
HyperlinkGene Summary
Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM
Other Designations
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Interactome
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Disease
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