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TNNI3 Validated Chimera RNAi

  • Catalog # : H00007137-R01V
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens troponin I type 3 (cardiac) (TNNI3), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000363
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of TNNI3 over-expressed 293 cell line, cotransfected with TNNI3 Validated Chimera RNAi ( Cat # H00007137-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with TNNI3 monoclonal antibody (M04), clone 1E7 (Cat # H00007137-M04 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
  • PDF DownloadProtocol Download
  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Entrez GeneID:
  • 7137
  • Gene Name:
  • TNNI3
  • Gene Alias:
  • CMD2A,CMH7,MGC116817,RCM1,TNNC1,cTnI
  • Gene Description:
  • troponin I type 3 (cardiac)
  • Gene Summary:
  • Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq
  • Other Designations:
  • familial hypertrophic cardiomyopathy 7,troponin I, cardiac
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