TNNI3 MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of TNNI3 expression in transfected 293T cell line (H00007137-T01) by TNNI3 MaxPab polyclonal antibody.
Lane 1: TNNI3 transfected lysate(23.1 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TNNI3 protein.
Immunogen
TNNI3 (AAH96165, 1 a.a. ~ 210 a.a) full-length human protein.
Sequence
MADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKKFES
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TNNI3 expression in transfected 293T cell line (H00007137-T01) by TNNI3 MaxPab polyclonal antibody.
Lane 1: TNNI3 transfected lysate(23.1 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — TNNI3
Entrez GeneID
7137GeneBank Accession#
BC096165Protein Accession#
AAH96165Gene Name
TNNI3
Gene Alias
CMD2A, CMH7, MGC116817, RCM1, TNNC1, cTnI
Gene Description
troponin I type 3 (cardiac)
Gene Ontology
HyperlinkGene Summary
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq
Other Designations
familial hypertrophic cardiomyopathy 7|troponin I, cardiac
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Interactome
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Pathway
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Disease
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