TNNI3 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant TNNI3.
Immunogen
TNNI3 (NP_000354, 102 a.a. ~ 210 a.a) partial recombinant protein with GST tag.
Sequence
ARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKKFES
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.1 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
TNNI3 polyclonal antibody (A01), Lot # 060110JC01. Western Blot analysis of TNNI3 expression in human ovarian cancer.Western Blot (Recombinant protein)
ELISA
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Gene Info — TNNI3
Entrez GeneID
7137GeneBank Accession#
NM_000363Protein Accession#
NP_000354Gene Name
TNNI3
Gene Alias
CMD2A, CMH7, MGC116817, RCM1, TNNC1, cTnI
Gene Description
troponin I type 3 (cardiac)
Gene Ontology
HyperlinkGene Summary
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq
Other Designations
familial hypertrophic cardiomyopathy 7|troponin I, cardiac
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Interactome
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Pathway
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Disease
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