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Last updated: 2016/10/23

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TNNI2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00007136-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TNNI2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 21.3
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TNNI2 antibody (H00007136-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00007136-T01
    TNNI2 transfected lysate.
    Western Blot
    QC Testing of H00007136-T01
    Lane 1: TNNI2 transfected lysate ( 21.30 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 7136
  • Gene Name:
  • TNNI2
  • Gene Alias:
  • Gene Description:
  • troponin I type 2 (skeletal, fast)
  • Gene Summary:
  • This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000014141,OTTHUMP00000014142,troponin I fast twitch 2,troponin I, fast-twitch skeletal muscle isoform,troponin I, skeletal, fast
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