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TNFRSF1B 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00007133-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-TNFRSF1B full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 50.82
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-TNFRSF1B antibody (H00007133-B01) by Western Blots.
    Western Blot
    QC Testing of H00007133-T01
    Lane 1: TNFRSF1B transfected lysate ( 48.3 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00007133-T01
    TNFRSF1B transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 7133
  • Gene Name:
  • TNFRSF1B
  • Gene Alias:
  • CD120b,TBPII,TNF-R-II,TNF-R75,TNFBR,TNFR1B,TNFR2,TNFR80,p75,p75TNFR
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 1B
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000001784,p75 TNF receptor,soluble TNFR1B variant 1,tumor necrosis factor beta receptor,tumor necrosis factor binding protein 2,tumor necrosis factor receptor 2
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