TNFAIP6 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFAIP6 full-length
Host
Human
Theoretical MW (kDa)
30.58
Interspecies Antigen Sequence
Mouse (92); Rat (91)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFAIP6 antibody (H00007130-B01) by Western Blots.
SDS-PAGE Gel
TNFAIP6 transfected lysate
Western Blot
Lane 1: TNFAIP6 transfected lysate ( 30.58 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TNFAIP6
Entrez GeneID
7130GeneBank Accession#
BC030205Protein Accession#
AAH30205Gene Name
TNFAIP6
Gene Alias
TSG-6, TSG6
Gene Description
tumor necrosis factor, alpha-induced protein 6
Omim ID
600410Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. The expression of this gene can be induced by tumor necrosis factor alpha and interleukin-1. The expression can also be induced by mechanical stimuli in vascular smooth muscle cells, and is found to be correlated with proteoglycan synthesis and aggregation. [provided by RefSeq
Other Designations
hyaluronate-binding protein|tumor necrosis factor alpha-inducible protein 6|tumor necrosis factor-inducible protein 6|tumor necrosis factor-stimulated gene-6 protein
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