TNFAIP3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TNFAIP3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TNFAIP3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TNFAIP3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TNFAIP3
Entrez GeneID
7128GeneBank Accession#
TNFAIP3Gene Name
TNFAIP3
Gene Alias
A20, MGC104522, MGC138687, MGC138688, OTUD7C, TNFA1P2
Gene Description
tumor necrosis factor, alpha-induced protein 3
Omim ID
191163Gene Ontology
HyperlinkGene Summary
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses. [provided by RefSeq
Other Designations
OTTHUMP00000017289|tumor necrosis factor inducible protein A20
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