CLDN5 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CLDN5 full-length ORF ( NP_003268.1, 1 a.a. - 218 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLCCGAWVCTGRPDLSFPVKYSAPRRPTATGDYDKKNYV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
49.5
Interspecies Antigen Sequence
Mouse (92); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CLDN5
Entrez GeneID
7122GeneBank Accession#
NM_003277.2Protein Accession#
NP_003268.1Gene Name
CLDN5
Gene Alias
AWAL, BEC1, CPETRL1, TMVCF
Gene Description
claudin 5
Omim ID
602101Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
androgen withdrawal and apoptosis induced protein RVP1-like|transmembrane protein deleted in velocardiofacial syndrome
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Interactome
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Pathway
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Disease
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