CLDN5 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (31.94 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CLDN5.
Immunogen
CLDN5 (NP_003268, 29 a.a. ~ 81 a.a) partial recombinant protein with GST tag.
Sequence
MWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAAR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.94 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CLDN5
Entrez GeneID
7122GeneBank Accession#
NM_003277Protein Accession#
NP_003268Gene Name
CLDN5
Gene Alias
AWAL, BEC1, CPETRL1, TMVCF
Gene Description
claudin 5
Omim ID
602101Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
androgen withdrawal and apoptosis induced protein RVP1-like|transmembrane protein deleted in velocardiofacial syndrome
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Interactome
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Pathway
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Disease
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Publication Reference
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Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways.
Escudero-Esparza A, Jiang WG, Martin TA.
Journal of Experimental & Clinical Cancer Research: CR 2012 May; 31(1):43.
Application：IF, IHC, Human, Human breast cancer, MDA-MB-231 cells.
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Claudin-5 participates in the regulation of endothelial cell motility.
Escudero-Esparza A, Jiang WG, Martin TA.
Molecular and Cellular Biochemistry 2012 Mar; 362(1-2):71.
Application：IF, Human, Human endothelial cell line HECV.
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Claudin-5 is involved in breast cancer cell motility through the N-WASP and ROCK signalling pathways.
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