TIMP3 monoclonal antibody (M01), clone 1D8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TIMP3.
Immunogen
TIMP3 (AAH14277, 112 a.a. ~ 211 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KMYTGLCNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TIMP3 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — TIMP3
Entrez GeneID
7078GeneBank Accession#
BC014277Protein Accession#
AAH14277Gene Name
TIMP3
Gene Alias
HSMRK222, K222, K222TA2, SFD
Gene Description
TIMP metallopeptidase inhibitor 3
Gene Ontology
HyperlinkGene Summary
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq
Other Designations
MIG-5 protein|tissue inhibitor of metalloproteinase 3
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Interactome
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Disease
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