TIAL1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human TIAL1 full-length ORF ( AAH30025.1, 1 a.a. - 252 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
54.3
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TIAL1
Entrez GeneID
7073GeneBank Accession#
BC030025.1Protein Accession#
AAH30025.1Gene Name
TIAL1
Gene Alias
MGC33401, TCBP, TIAR
Gene Description
TIA1 cytotoxic granule-associated RNA binding protein-like 1
Omim ID
603413Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq
Other Designations
OTTHUMP00000020602|OTTHUMP00000020605|T-cluster binding protein|TIA-1 related protein|TIA-1-related nucleolysin|TIA1 cytotoxic granule-associated RNA-binding protein-like 1|aging-associated gene 7 protein
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Interactome
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