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Last updated: 2016/12/4

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TIA1 rabbit monoclonal antibody

  • Catalog # : H00007072-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TIA1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TIA1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TIA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7072
  • GeneBank Accession#:
  • TIA1
  • Gene Name:
  • TIA1
  • Gene Alias:
  • -
  • Gene Description:
  • TIA1 cytotoxic granule-associated RNA binding protein
  • Gene Summary:
  • The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq
  • Other Designations:
  • T-cell-restricted intracellular antigen-1,TIA1 cytotoxic granule-associated RNA-binding protein,TIA1 protein,cytotoxic granule-associated RNA-binding protein,nucleolysin TIA-1 isoform p40,p40-TIA-1 (containing p15-TIA-1)
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