THBD DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human THBD DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — THBD
Entrez GeneID
7056GeneBank Accession#
NM_000361.2Protein Accession#
NP_000352.1Gene Name
THBD
Gene Alias
CD141, THRM, TM
Gene Description
thrombomodulin
Omim ID
188040Gene Ontology
HyperlinkGene Summary
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq
Other Designations
CD141 antigen|OTTHUMP00000030415|fetomodulin
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Interactome
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Pathway
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Disease
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