TGM2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
TGM2 transfected lysate.
Western Blot
Lane 1: TGM2 transfected lysate ( 61.70 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TGM2 full-length
Host
Human
Theoretical MW (kDa)
61.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TGM2 antibody (H00007052-D01P) by Western Blots.
SDS-PAGE Gel
TGM2 transfected lysate.
Western Blot
Lane 1: TGM2 transfected lysate ( 61.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TGM2
Entrez GeneID
7052GeneBank Accession#
NM_198951Protein Accession#
NP_945189.1Gene Name
TGM2
Gene Alias
G-ALPHA-h, GNAH, TG2, TGC
Gene Description
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
Omim ID
190196Gene Ontology
HyperlinkGene Summary
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
C polypeptide|OTTHUMP00000030960|TGase C|TGase-H|protein-glutamine-gamma-glutamyltransferase|tissue transglutaminase|transglutaminase 2|transglutaminase C
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Interactome
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Disease
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