TGM2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human TGM2 partial ORF ( AAH03551, 1 a.a. - 120 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
38.83
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TGM2
Entrez GeneID
7052GeneBank Accession#
BC003551Protein Accession#
AAH03551Gene Name
TGM2
Gene Alias
G-ALPHA-h, GNAH, TG2, TGC
Gene Description
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
Omim ID
190196Gene Ontology
HyperlinkGene Summary
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
C polypeptide|OTTHUMP00000030960|TGase C|TGase-H|protein-glutamine-gamma-glutamyltransferase|tissue transglutaminase|transglutaminase 2|transglutaminase C
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Interactome
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Disease
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