TGM1 (Human) Recombinant Protein (Q01)

Catalog # H00007051-Q01

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Size:25 ug
Price: USD $ 510.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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  • Specification

    Product Description

    Human TGM1 partial ORF ( NP_000350.1, 146 a.a. - 245 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    PFHMLLLLSRTYESSDRITLELLIGNNPEVGKGTHVIIPVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNEIYI

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    36.74

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — TGM1

    Entrez GeneID

    7051

    GeneBank Accession#

    NM_000359

    Protein Accession#

    NP_000350.1

    Gene Name

    TGM1

    Gene Alias

    ICR2, KTG, LI, LI1, TGASE, TGK

    Gene Description

    transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)

    Omim ID

    190195 242100 242300

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq

    Other Designations

    TGase K|epidermal TGase|transglutaminase 1|transglutaminase K|transglutaminase, keratinocyte

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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