TGM1 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of TGM1 expression in transfected 293T cell line (H00007051-T01) by TGM1 MaxPab polyclonal antibody.
Lane 1: TGM1 transfected lysate(89.87 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to TGM1 on formalin-fixed paraffin-embedded human uterine cervix. [antibody concentration 3 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TGM1 protein.
Immunogen
TGM1 (AAH34699, 1 a.a. ~ 817 a.a) full-length human protein.
Sequence
MMDGPRSDVGRWGGNPLQPPTTPSPEPEPEPDGRSRRGGGRSFWARCCGCCSCRNAADDDWGPEPSDSRGRGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGNNPEVGKGTHVIIPVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAVMGQDLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of TGM1 expression in transfected 293T cell line (H00007051-T01) by TGM1 MaxPab polyclonal antibody.
Lane 1: TGM1 transfected lysate(89.87 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to TGM1 on formalin-fixed paraffin-embedded human uterine cervix. [antibody concentration 3 ug/ml] -
Gene Info — TGM1
Entrez GeneID
7051GeneBank Accession#
BC034699Protein Accession#
AAH34699Gene Name
TGM1
Gene Alias
ICR2, KTG, LI, LI1, TGASE, TGK
Gene Description
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). [provided by RefSeq
Other Designations
TGase K|epidermal TGase|transglutaminase 1|transglutaminase K|transglutaminase, keratinocyte
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Interactome
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Disease
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Publication Reference
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A Harungana madagascariensis extract with retinol-like properties - Gene upregulations and protein expressions in human fibroblasts and skin explants.
Richard Fitoussi, Marie-Christine Branchet, Natacha Garnier, Gallic Beauchef, Alex Nkengne, Katell Vié, Sylvie Boisnic.
International Journal of Cosmetic Science 2022 Apr; 44(2):201.
Application：IHC, Human, Human skin.
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Ectopic transglutaminase 1 and 3 expression accelerating keratinization in oral lichen planus.
Shimada K, Ochiai T, Hasegawa H.
The Journal of International Medical Research 2018 Sep; 300060518798261.
Application：IHC-P, Human, Oral lichen planus.
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A Harungana madagascariensis extract with retinol-like properties - Gene upregulations and protein expressions in human fibroblasts and skin explants.
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