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TGIF Pre-design Chimera RNAi

  • Catalog # : H00007050-R04
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens TGFB-induced factor (TALE family homeobox) (TGIF), transcript variant 3, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_173208
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 7050
  • Gene Name:
  • TGIF1
  • Gene Alias:
  • HPE4,MGC39747,MGC5066,TGIF
  • Gene Description:
  • TGFB-induced factor homeobox 1
  • Gene Summary:
  • The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described. [provided by RefSeq
  • Other Designations:
  • 5'-TG-3' interacting factor,TALE homeobox TG-interacting factor,TG-interacting factor,homeobox protein TGIF,transforming growth factor-beta-induced factor
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