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Last updated: 2016/12/4
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TGIF polyclonal antibody (A01)

  • Catalog # : H00007050-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant TGIF.
  • Immunogen:
  • TGIF (NP_003235, 163 a.a. ~ 272 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • PGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQNTDIQQIAAKNFTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00007050-A01
    Western Blot detection against Immunogen (38.21 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • TGIF polyclonal antibody (A01), Lot # 051017JC01 Western Blot analysis of TGIF expression in Y-79 ( Cat # L042V1 ).
  • PDF DownloadProtocol Download
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7050
  • Gene Name:
  • TGIF1
  • Gene Alias:
  • HPE4,MGC39747,MGC5066,TGIF
  • Gene Description:
  • TGFB-induced factor homeobox 1
  • Gene Summary:
  • The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described. [provided by RefSeq
  • Other Designations:
  • 5'-TG-3' interacting factor,TALE homeobox TG-interacting factor,TG-interacting factor,homeobox protein TGIF,transforming growth factor-beta-induced factor
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