TGFBR1 (Human) Recombinant Protein (Q01)
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More Files
- More Functions
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Specification
Product Description
Human TGFBR1 partial ORF ( NP_004603, 30 a.a. - 125 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GATALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPGLGPVE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.3
Interspecies Antigen Sequence
Mouse (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TGFBR1
Entrez GeneID
7046GeneBank Accession#
NM_004612Protein Accession#
NP_004603Gene Name
TGFBR1
Gene Alias
AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, SKR4, TGFR-1
Gene Description
transforming growth factor, beta receptor 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000021783|activin A receptor type II-like kinase, 53kD|activin A receptor type II-like kinase, 53kDa|activin receptor-like kinase 5|serine/threonine-protein kinase receptor R4|transforming growth factor beta receptor I|transforming growth factor,
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Interactome
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Pathway
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Disease
- Abnormalities
- Adenocarcinoma
- Adenoma
- Aneurysm
- Aortic Aneurysm
- Aortic Rupture
- Asthma
- Atherosclerosis
- Behcet Syndrome
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