TGFBI 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TGFBI full-length
Host
Human
Theoretical MW (kDa)
75.24
Interspecies Antigen Sequence
Mouse (91); Rat (90)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TGFBI antibody (H00007045-B01) by Western Blots.
Western Blot
Lane 1: TGFBI transfected lysate ( 75.13 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
TGFBI transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TGFBI
Entrez GeneID
7045GeneBank Accession#
BC000097Protein Accession#
AAH00097Gene Name
TGFBI
Gene Alias
BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, LCD1
Gene Description
transforming growth factor, beta-induced, 68kDa
Gene Ontology
HyperlinkGene Summary
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq
Other Designations
RGD-containing collagen-associated protein|kerato-epithelin
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Interactome
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Disease
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