Immunoprecipitation of TGFBI transfected lysate using anti-TGFBI MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with TGFBI MaxPab rabbit polyclonal antibody (D01) (H00007045-D01).
This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq