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Latent TGFB1 monoclonal antibody (M08), clone 2F10

  • Catalog # : H00007040-M08
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of human TGFB1.
  • Immunogen:
  • Synthetic peptide of human TGFB1.
  • Sequence:
  • Immunogen sequence information is proprietary.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • WB result shows no cross reaction with recombinant TGFB2 and TGFB3 proteins.
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Latent TGFB1 monoclonal antibody (M08), clone 2F10. Western Blot analysis of TGFB1 expression in HepG2.
  • PDF DownloadProtocol Download
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Latent TGFB1 monoclonal antibody (M08), clone 2F10. Western Blot analysis of TGFB1 expression in MCF-7.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of TGFB expression in transfected 293T cell lines by Latent TGFB1 monoclonal antibody (M08), clone 2F10.

    Lane 1: TGFB1 transfected lysate.
    Lane 2: TGFB2 transfected lysate.
    Lane 3: TGFB3 transfected lysate.
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  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) enlargeenlarge this image
  • Immunohistochemical staining of various tissues with hematoxylin and Latent TGFB1 monoclonal antibody, clone 2F10.

    ( a ) Human hepatocellular carcinoma
    ( b ) Human lung adenocarcinoma
    ( c ) Human breast cancer
    ( d ) Human prostate cancer
    ( e ) Wild-type mouse lung
    ( f ) TGFB1 transgenic mouse lung
  • PDF DownloadProtocol Download
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7040
  • Gene Name:
  • TGFB1
  • Gene Alias:
  • CED,DPD1,TGFB,TGFbeta
  • Gene Description:
  • transforming growth factor, beta 1
  • Gene Summary:
  • TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA (MIM 190170) in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 (MIM 190220), and TGFB3 (MIM 190230) all function through the same receptor signaling systems.[supplied by OMIM
  • Other Designations:
  • TGF-beta 1 protein,diaphyseal dysplasia 1, progressive,transforming growth factor-beta 1
  • Interactome
  • Interactome
  • Related Disease
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