TFR2 monoclonal antibody (M01), clone 3C5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TFR2.
Immunogen
TFR2 (NP_003218, 631 a.a. ~ 731 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IRLSHDRLLPLDFGRYGDVVLRHIGNLNEFSGDLKARGLTLQWVYSARGDYIRAAEKLRQEIYSSEERDERLTRMYNVRIMRVEFYFLSQYVSPADSPFR*
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — TFR2
Entrez GeneID
7036GeneBank Accession#
NM_003227Protein Accession#
NP_003218Gene Name
TFR2
Gene Alias
HFE3, MGC126368, TFRC2
Gene Description
transferrin receptor 2
Gene Ontology
HyperlinkGene Summary
This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
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Interactome
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Disease
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